Exposure to high levels of ethylbenzene in air for short periods can cause eye and throat irritation. Exposure to higher levels can result in dizziness.
Irreversible damage to the inner ear and hearing has been observed in animals exposed to relatively low concentrations of ethylbenzene for several days to weeks.
Exposure to relatively low concentrations of ethylbenzene in air for several months to years causes kidney damage in animals.
The International Agency for Research on Cancer (IARC) has determined that ethylbenzene is a possible human carcinogen.